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--- antihystamines [2025.07.29 16:25] – Steve Isenberg
+++ antihystamines [2025.07.29 16:42] (current) – Steve Isenberg
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   * If you’re older (65+) or have concerns about cognition, stick with second-generation options
+===== Is Sudafed an Antihistamine? =====
+No — Sudafed is not an antihistamine. It is a decongestant, though it’s often used alongside antihistamines to treat cold or allergy symptoms.
+⸻
+==== 🧪 What Is Sudafed? ====
+Sudafed is the brand name for:
+  * ‘‘Pseudoephedrine’’ – the original version, available behind the pharmacy counter
+  * ‘‘Phenylephrine’’ – an over-the-counter version that is less effective
+It’s classified as a nasal decongestant.
+⸻
+==== 💊 How It Works ====
+Decongestants like Sudafed:
+  * Constrict blood vessels in the nasal passages
+  * Reduce swelling and improve airflow
+  * Do not block histamine
+Antihistamines:
+  * Block histamine, the chemical responsible for sneezing, itching, and watery eyes
+^ Symptom ^ Use Antihistamine? ^ Use Decongestant (Sudafed)? ^
+| Sneezing | ✅ Yes | ❌ No |
+| Itchy eyes or nose | ✅ Yes | ❌ No |
+| Runny nose | ✅ Yes | ❌ Not directly |
+| Nasal congestion | ❌ Not effective | ✅ Yes |
+⸻
+==== ⚠️ Warnings About Sudafed ====
+  * Can raise blood pressure – not ideal for people with hypertension or heart disease
+  * May cause jitters, restlessness, or insomnia
+  * Pseudoephedrine is regulated — you must request it from the pharmacy counter and show ID
+  * Phenylephrine, found in many OTC products, has been shown to be ineffective when taken orally (per FDA findings)
+⸻
+==== 🔄 Combination Medications ====
+Some allergy medications combine antihistamines with Sudafed, such as:
+  * Claritin-D (loratadine + pseudoephedrine)
+  * Zyrtec-D (cetirizine + pseudoephedrine)
+These treat both:
+  * Histamine symptoms – sneezing, itching, watery eyes
+  * Nasal congestion
+⸻
+==== ✅ Bottom Line ====
+  * Sudafed is a decongestant, not an antihistamine
+  * Best for nasal congestion, not for sneezing or itchy eyes
+  * Can be used alongside antihistamines for broader relief
+  * Use with caution if you have heart conditions, high blood pressure, or insomnia